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Lennox Tip: Allergy relief is one of the major benefits of an air purifier, but you should consider the placement of portable purifiers carefully. It's a very good idea to put an air purifier in the same area as a litter box, as these are high concentrations of allergens. Even a smaller portable can help reduce the allergen problem near a litter box or housebreaking area. Also be sure to vacuum such areas often, and use a vacuum with a HEPA filter for maximum allergy relief.